Dose-response relationships modelled by dose response curves are used extensively in pharmacology and drug development. In particular, the shape of a drug's dose–response …

Dose-response, which involves the principles of pharmacokinetics and pharmacodynamics, determines the required dose and frequency as well as the therapeutic index for a drug in a …

A dose-response relationship is one in which increasing levels of exposure are associated with either an increasing or a decreasing risk of the outcome. Demonstration of a dose-response …

This review introduces a cautionary framework for investigators considering dose–response relationships in observational research to support evidence-based medicine. Each pitfall is …

Dec 27, 2025 · The dose-response relationship is a fundamental concept in pharmacology that describes how the effects of a drug change with varying doses. This relationship is crucial for …

The dose–response relationship, or exposure–response relationship, describes the change in effect on an organism caused by differing levels of exposure (or doses) to a stressor (usually a …

Jan 28, 2025 · Dose-response relationships When the relation between drug dose (X-axis) and drug response (Y-axis) is plotted on a linear scale, the resulting curve is usually hyperbolic. …

A dose-response curve visually depicts the relationship between a substance’s concentration (dose) and the effect it produces in a biological system. The dose is plotted on the horizontal …

The dose-response relationship demonstrates whether any effect has occurred, the threshold dose, and the rate at which the effect increases with increasing dose levels.

The dose-response relationship describes the correlation between the amount of exposure to a substance (the dose) and the magnitude of the response or effect it produces in a population.