Background Systemic lupus erythematosus (SLE) predominantly affects women of childbearing age and is often associated with ...

Objectives The intrauterine environment may influence childhood immune-mediated disease risk. We investigated whether ...

Background Approximately 10%–20% of patients with Kawasaki disease (KD) are resistant to intravenous immunoglobulins (IVIG) ...

It is postulated that fibromyalgia reflects a neurobiologically rooted imbalance between overactivated threat systems and ...

Objectives The oral microbiome plays a critical role in modulating systemic inflammation, partly through its interactions ...

Objectives Medication adherence is a key determinant of treatment effectiveness in chronic inflammatory diseases but data in ...

Background The diagnosis of antiphospholipid syndrome (APS) uses standard antibodies (lupus anticoagulant (LAC), anticardiolipin antibodies (aCL) IgG/IgM, β2-glycoprotein I antibodies (β2GPI) IgG/IgM) ...

Objectives Patients with primary Sjögren’s disease (SjD) have an increased risk of B cell lymphoma. The aim of this study was to determine serum protein biomarkers for lymphoma development and to ...

Objectives To investigate the association of diabetes, hypertension and overweight/obesity with physical activity (PA), self-efficacy for pain and self-efficacy for other symptoms before and after a 6 ...

Background About 20% of female patients with anti-phospholipid syndrome (APS) experience obstetric complications despite standard treatment with aspirin and heparin. Treatment with hydroxychloroquine ...

Objectives Systemic autoinflammatory diseases (SAIDs) represent a set of conditions with exaggerated innate immune responses. IL-1β and IL-18 are key cytokines involved in the pathogenesis of some ...

Objectives To determine belimumab efficacy assessed using the British Isles Lupus Assessment Group (BILAG)-based Combined Lupus Assessment (BICLA) in patients with systemic lupus erythematosus (SLE) ...