UPDATE: The scene cleared around 5 a.m. Officers said after making entry into the apartment, the suspect was not found. Authorities in Greenville, South Carolina, are trying to get a barricaded person ...

A man and woman have been charged after authorities removed 42 dogs from deplorable conditions at a South Carolina home.At 11:30 p.m. Wednesday, deputies with the Laurens County Sheriff's Office ...

On this Independence Day holiday, Upstate veterinarians are stressing the importance of keeping pets calm and collected. They ...

Skinner watched U.S. Immigration and Customs Enforcement officers put Jian Hao Zhang in the van, leaving his wife and two ...

Upstate Medical University is holding a groundbreaking ceremony for a new, state-of-the-art laboratory called the Upstate ...

The parents were convicted of exposing the infant to extreme heat and cold and witholding needed nourishment, which caused ...

Bombshell court filings shed new light on a situation that roiled the city of Cohoes, which is located about 150 miles north ...

Pickens County’s first and only homeless shelter, that’s helped thousands for nearly a decade, may lose its home after the ...

Two youth baseball coaches have been fired after they were filmed stripping naked and streaking at an upstate New York ...

Fountain Inn, Lake Keowee, Landrum, Spartanburg and Westminster are home to the 7 most expensive residential real estate home listings in Upstate, SC.

Two other upstate waterways, one in Western New York and one in the Adirondacks, also made the list of the nation's best ...

Upstate festivals this summer have something for everyone, from music to plays to food and more. Here's when, where and how ...