Background Systemic lupus erythematosus (SLE) predominantly affects women of childbearing age and is often associated with ...

Objectives The oral microbiome plays a critical role in modulating systemic inflammation, partly through its interactions ...

Objectives The intrauterine environment may influence childhood immune-mediated disease risk. We investigated whether ...

Background Approximately 10%–20% of patients with Kawasaki disease (KD) are resistant to intravenous immunoglobulins (IVIG) ...

It is postulated that fibromyalgia reflects a neurobiologically rooted imbalance between overactivated threat systems and ...

Objectives Medication adherence is a key determinant of treatment effectiveness in chronic inflammatory diseases but data in ...

Background In SELECT-PsA 1, a randomised double-blind phase 3 study, upadacitinib 15 mg and 30 mg were superior to placebo and non-inferior to adalimumab in ≥20% improvement in American College of ...

Emerging evidence suggests that axial spondyloarthritis (axSpA) should not be seen as a predominantly male disease, as the non-radiographic form occurs with roughly equal frequency in women and men.

Psoriatic arthritis (PsA) is a chronic inflammatory disease characterised by joint involvement, significant impact on quality of life and frequently linked with obesity, metabolic syndrome and ...

Objectives The gut microbiota can mediate both pro and anti-inflammatory responses. In patients with psoriatic arthritis (PsA), we investigated the impact of faecal microbiota transplantation (FMT), ...

Objective Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly recognised for benefits beyond glycaemic control, including anti-inflammatory, anti-atherogenic and potential ...

Introduction Despite better therapies and strategies, many people with rheumatoid arthritis (RA) have persistent pain, often from abnormal pain processing, now termed nociplastic pain. However, RA ...