GutOpinion

Deferring first surveillance to 3 years after colorectal ESD is not supported by these data

Qatomah and colleagues conclude that the first surveillance colonoscopy (SC1) after colorectal endoscopic submucosal ...
Gut

Macropinocytosis of neutrophil extracellular trap by gastric cancer cells promotes immune escape and peritoneal metastasis

Background Patients with gastric cancer (GC) and peritoneal metastasis (PM) have poor prognoses due to drug resistance and ...
Gut

Impact of initial severity and progression pattern of new-onset diabetes on pancreatic cancer risk: a 15-year longitudinal nationwide cohort study

Background New-onset diabetes (NOD) increases the risk of pancreatic cancer. Previous studies have mainly focused on the ...
Gut

Faecal proteases and immune signatures drive subtype-specific enteric neuronal activation in IBS

Background Luminal proteases have been implicated in epithelial barrier dysfunction and visceral hypersensitivity in ...
gut.bmj

DR1-DR2 enrichment in HBeAg-negative chronic hepatitis B: integration hotspot or survivor signature?

We read with great interest the recent study by Lau et al, who reported distinct intrahepatic hepatitis B virus (HBV) integration patterns according to HBeAg status and observed marked enrichment of ...
gut.bmj

LY6D identifies persistent stem-like cells driving pancreatic tumourigenesis

Background Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterised by remarkable cellular heterogeneity, which emerges early from the interplay of oncogenic KRAS ...
gut.bmj

Spatial single-cell omics in liver studies: cautions on metanarrative pitfalls

We read with great interest the review by Suo et al published in Gut recently, ‘Spatial single-cell omics: new insights into liver diseases’.1 This very well-written and comprehensive review ...