Researchers have uncovered a previously hidden layer of complexity in how genes are activated, showing that water molecules ...

Gene syntax alters DNA supercoiling to amplify or suppress nearby genes. This could improve the effectiveness of gene ...

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and ...

EM, researchers showed that water mediates catalysis and important protein interactions for RNA polymerase II function in ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

This month, Prof. Franklin Pugh, molecular biology and genetics, and researchers Chitvan Mittal grad, Olivia Lang grad, and William K.M. Lai grad, found that inducible systems work in conjunction with ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular senescence—a state where cells stop dividing but remain metabolically active.

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that ...