The 49ers kicked off their practice week with Mac Jones on the field and Brock Purdy off of it. Head coach Kyle Shanahan said that Jones will be listed as a limited participant because of knee and ...

Along with suffering a dislocated ankle Sunday against the Philadelphia Eagles, New York Giants running back also fractured ...

The Los Angeles Chargers have signed defensive lineman Kyle Peko and safety Marcus Williams to the practice squad. Peko is a ...

INGLEWOOD, Calif. - With the San Francisco 49ers M*A*S*H unit staying busy and missing several frontline starters due to injury, who could blame NFL oddsmakers for making them heavy 8.5-point ...

The 49ers (4-2) lost Fred Warner to a first-quarter ankle injury and went on to lose 30-19 to the host Tampa Bay Buccaneers.

The San Francisco 49ers had a challenging afternoon in their 26-15 loss on October 26 to the Houston Texans at NRG Stadium.

SANTA CLARA, Calif. (AP) — The San Francisco 49ers went through another day of preparation for their game against Tampa Bay without either of their top two quarterbacks healthy enough to throw the ...

The 49ers couldn’t overcome their season-long injury issues Sunday as they fell in Tampa to the Buccaneers 30-19. Fred Warner went down with a gruesome ankle injury in the first quarter, leaving the ...