BMJ

EEG to detect early recovery of consciousness in amantadine-treated acute brain injury patients

Disorder of consciousness (DOC) is common in patients with acute brain injury (ABI) and it weighs heavily in goals of care discussion.1 Dopaminergic agents to support recovery have shown encouraging ...
BMJ

Interstitial laser anterior capsulotomy for obsessive–compulsive disorder: lesion size and tractography correlate with outcome

Correspondence to Professor Peter Warnke, Neurosurgery, University of Chicago Biological Sciences Division, Chicago, IL 60637, USA; pwarnke{at}surgery.bsd.uchicago.edu Background Anterior capsulotomy ...
BMJ

Nusinersen safety and effects on motor function in adult spinal muscular atrophy type 2 and 3

Objective To retrospectively investigate safety and efficacy of nusinersen in a large cohort of adult Italian patients with spinal muscular atrophy (SMA). Methods Inclusion criteria were: (1) clinical ...
BMJ

Structural and functional changes in the retina in Parkinson’s disease

Parkinson’s disease is caused by degeneration of dopaminergic neurons, originating in the substantia nigra pars compacta and characterised by bradykinesia, rest tremor and rigidity. In addition, ...
BMJ

What is the optimal dose of botulinum toxin A in the treatment of cervical dystonia? Results of a double blind, placebo controlled, dose ranging study using Dysport

Professor G Deuschl, Neurologische Klinik der Christian-Albrechts-Universität, Niemannsweg 147, D-24105 Kiel, Germany. Telephone 0049 431 597 2610; fax 0049 431 597 2712. OBJECTIVES Botulinum toxin ...
BMJ

Distinct behavioural profiles in frontotemporal dementia and semantic dementia

OBJECTIVE To test predictions that frontotemporal dementia and semantic dementia give rise to distinct patterns of behavioural change. METHODS An informant based semistructured behavioural interview, ...
BMJ

What are the determinants of quality of life in people with cervical dystonia?

Background: Little is known about the quality of life in patients with cervical dystonia, although pain and depression are relatively common. Objective: To test the hypothesis that an individual's ...
BMJ

Survival in memory clinic cohort is short, even in young-onset dementia

Correspondence to Hanneke Frederica Maria Rhodius-Meester, Alzheimer Center, VU University Medical Center, Amsterdam 1007 MB, The Netherlands; h.rhodius{at}vumc.nl Patients with dementia have a ...
BMJ

Education and rates of cognitive decline in incident Alzheimer’s disease

1 Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer’s Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA 2 The Gertrude H Sergievsky ...
BMJ

Neurology of the pituitary gland

aDepartment of Neuropathology, Box 235, bDepartment of Neuroradiology, Box 219, cDepartment of Neuro-oncology, Box 193, dDepartment of Diabetes and Endocrinology Box 157, eDepartment of Diabetes and ...
BMJ

Global aphasia without hemiparesis: language profiles and lesion distribution

Dr Robert Hanlon, Department of Psychiatry, Northwestern University Medical School, 303 E Superior Street, 5th Floor, Chicago, IL 60611, USA OBJECTIVES Global aphasia without hemiparesis (GAWH) is an ...
BMJ

Measuring change in disability after inpatient rehabilitation: comparison of the responsiveness of the Barthel Index and the Functional Independence Measure

Professor AJ Thompson, Institute of Neurology, Queen Square, London WC1N 3BG, UK. Telephone 0044 171 837 3611 ext 4152; fax 0044 171 813 6505; email athompson{at}ion.ucl.ac.uk BACKGROUND The ...