A shooting that left one person injured is under investigation in Spartanburg County, South Carolina. Deputies with the ...

Spartanburg Regional Healthcare System launched a new obstetrics and gynecology (OB/GYN) residency program in 2025 to train ...

The state has rated at least seven spans in Greenville County, five in Spartanburg County, and two in Anderson County in need ...

Demand for commercial construction in Upstate SC remains strong, but labor shortages challenge the industry’s ability to keep ...

Audrey Frey is the senior managing director and market leader for CBRE’s South Carolina business. She oversees business ...

An Oconee County, South Carolina, man has been charged in connection with a sexual assault investigation. On June 5, deputies ...

Gospel, bluegrass, hip hop and soul music are all represented in live entertainment options across the Upstate this August.

Pickens County, a rural spread of 133,462 people, is where Trump won by the largest margin in South Carolina in 2016 and 2020, making the Upstate his friendliest political territory in South Carolina.

GREENVILLE, S.C. (FOX Carolina) - Families of two men who died at the hands of an upstate serial killer are demanding action ...

A heat dome has engulfed the South, Midwest, and East, bringing oppressive temperatures that are forecast to linger in the ...

"There are almost 6 million people in this state and there are 18 dairy farms. When we started in '78, there was right around 500." ...

The South Carolina Gamecocks play host to USC Upstate for a midweek matchup on Tuesday evening. Here's how to watch the matchup. The South Carolina Gamecocks baseball season hasn't exactly gone ...