Background Systemic lupus erythematosus (SLE) predominantly affects women of childbearing age and is often associated with ...

Objectives The oral microbiome plays a critical role in modulating systemic inflammation, partly through its interactions ...

Objectives The intrauterine environment may influence childhood immune-mediated disease risk. We investigated whether ...

Background Approximately 10%–20% of patients with Kawasaki disease (KD) are resistant to intravenous immunoglobulins (IVIG) ...

It is postulated that fibromyalgia reflects a neurobiologically rooted imbalance between overactivated threat systems and ...

Objectives Medication adherence is a key determinant of treatment effectiveness in chronic inflammatory diseases but data in ...

Objectives To assess 52-week safety and efficacy of bimekizumab in patients with active psoriatic arthritis (PsA) and prior inadequate response/intolerance to tumour necrosis factor inhibitors.

Background Vascular inflammation persists in temporal artery biopsy (TAB) of giant cell arteritis (GCA) patients even after prolonged glucocorticoid (GC) therapy. We aimed to evaluate the histological ...

Background Physical activity (PA) in rheumatoid arthritis (RA) is considered a cornerstone in the treatment. To highlight aspects involved in supporting a positive PA behaviour, it is important to ...

Background In SELECT-PsA 1, a randomised double-blind phase 3 study, upadacitinib 15 mg and 30 mg were superior to placebo and non-inferior to adalimumab in ≥20% improvement in American College of ...

The therapeutic window of opportunity in rheumatoid arthritis (RA) is often referred to. However, some have questioned whether such a period, in which the disease is more susceptible to ...

Emerging evidence suggests that axial spondyloarthritis (axSpA) should not be seen as a predominantly male disease, as the non-radiographic form occurs with roughly equal frequency in women and men.