Cancers are populations of cells that are heterogeneous across space and through time. This diversity is currently a major clinical issue, limiting the efficiency of most cancer treatments as there is ...

Model organisms are key to understanding principles of animal function and adaptation, although they are singular representatives of their lineages and biodiversity. Here, we propose considering model ...

Cleveland Clinic researchers are working to improve the way we use evolutionary modeling to understand drug resistance. The study, published in Science Advances, uses a new type of evolutionary model ...

Evolution is traditionally associated with a process of increasing complexity and gaining new genes. However, the explosion of the genomic era shows that gene loss and simplification is a much more ...

An updated evolutionary model shows that living systems evolve in a split-and-hit-the-gas dynamic, where new lineages appear in sudden bursts rather than during a long marathon of gradual changes.