A case study reviews the reformulation and scale up of high drug load prototype using wet granulation process for a model formulation. The reformulation of a 100-mg tablet into a 300-mgtablet ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

Continuous twin-screw granulation offers several options for increasing production scale. Thermo Fisher Scientific explains factors to consider in scale-up projects for manufacturing oral solid-dosage ...

Pharmaceutical research and development (R&D) and industry require a continuous fluid-bed dryer that provides a lengthy process time and delivers a high standard for a long time. This article ...