People's bodies can be old or young for their chronological age, depending, in part, on the amount and types of stressors they have experienced. Scientists can estimate people's biological age, but ...

Researchers have developed a novel technology that allows the distribution of components within a single cell to be accurately detected and visualized. Positioning a t-SPESI (tapping-mode scanning ...

Single-cell omics technologies enable characterizing the cellular complexity of biological samples with very high resolution. While individual samples can provide readouts for thousands of individual ...

Biobanks are valuable service units that ensure the usage of high-quality biological samples. They contribute to translational research, and their support may improve future therapeutic approaches.

Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...

Discover practical strategies for analyzing challenging biological samples, from low-input and degraded specimens to complex matrices.

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged ...

Scientists from the Chinese Academy of Sciences and Monash University report that they have developed a new method to measure biological aging in individual cell types. The new tool offers a more ...

Depth degradation is a problem biologists know all too well: The deeper you look into a sample, the fuzzier the image becomes. A worm embryo or a piece of tissue may only be tens of microns thick, but ...

In a recent study published in the journal Nature Aging, researchers in Singapore and the United States conducted comprehensive profiling of a longitudinal cohort (n = 108) using next-generation multi ...