Objectives Owing to the underrepresentation of early-stage disease in randomised trials and inconsistent clinical evidence, ...

Here we review target trial emulation to supplement evidence from randomized trials and inform regulatory and clinical decision making in oncology. Understanding the strengths and limitations of the ...

Breast cancer survivors who maintain an exercise routine suited to their personal needs may improve their long-term survival, a new study suggests. The study, designed as a so-called target trial ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Researchers conducted a retrospective cohort study comparing the effectiveness and safety of abatacept vs rituximab for RA-ILD using an emulated target trial design, with data obtained from the ...

Using statins for primary prevention is safe and beneficial in adults with type 2 diabetes irrespective of their estimated 10-year risk of cardiovascular disease at baseline, a target trial emulation ...

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