Here, we have focused primarily on just one aspect of the complex regulation of the Bax and Bak death effectors: that of their regulated insertion into the MOM, as a pre-condition for their subsequent ...
Bid, a pro-apoptotic member of the Bcl-2 family, was initially discovered through binding to both pro-apoptotic Bax and anti-apoptotic Bcl-2. During apoptosis, Bid can be cleaved not only by caspase-8 ...
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