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Single nucleotide polymorphism (SNP) interaction plays a critical role for complex diseases. The primary limitation of logistic regressions (LR) in testing SNP–SNP interactions is that coefficient ...
This example illustrates some properties of splines. Splines are curves, which are usually required to be continuous and smooth. Splines are usually defined as piecewise polynomials of degree n with ...
The missing portions of variables subjected to SPLINE or MSPLINE transformations are handled the same way as for OPSCORE, MONOTONE, UNTIE, and LINEAR transformations (see the previous section). The ...
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