Splenomegaly is one of the characteristic signs of an overactive spleen. It can cause platelets to pool inside of your spleen and cause thrombocytopenia. Thrombocytopenia is when you have a low ...

A recent study found that higher spleen volume before undergoing allogeneic hematopoietic stem cell transplantation (HSCT) was associated with worse overall survival and higher nonrelapse mortality ...

Patients with myelofibrosis had clinically significant improvement in disease-related symptoms, including anemia and spleen enlargement, when treated with the targeted therapy momelotinib, according ...

Thrombocytopenia (low platelet count) is common in people with cirrhosis. Possible causes include an enlarged spleen and decreased platelet production. Severe thrombocytopenia can increase the risk of ...

Amsterdam, the Netherlands — In a multivariate analysis of compensated cirrhotic patients infected with hepatitis C virus, spleen stiffness and model for end-stage liver disease (MELD) score emerged ...

Pain under the left rib cage can be a sign of a heart attack, which is a medical emergency. An enlarged or ruptured spleen, which may result from trauma, can cause sharp pain. Kidney infections can ...