Lipid nanoparticle formulation has increased over the past two decades. LNPs have proven to be effective nano-based delivery vehicles for cytotoxic chemotherapeutic drugs, nucleic acid therapies and ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

The earliest iteration of LNPs was the development of liposomes in the 1960s, with the first liposome-based drug product, Doxil, receiving FDA approval in 1995. In the early 1990s, a second generation ...

Product Performance – potency and dosing: Cryogenic transmission electron microscopy (Cryo-TEM) revealed more uniform, solid-core particles. Increased lipid and RNA concentrations can enhance in vivo ...

Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big impact on how well our cells absorb them, paving the way to more efficient ...

LNPs consist of ionizable lipids, which are critical for encapsulating RNA and enabling cellular uptake. Helper lipids contribute to the structural integrity and fusion with cell membranes.

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable ...

In a review article published in the journal Foods, researchers in Italy have illustrated the neuroprotective role of curcumin and curcumin-containing nanoparticles in neurodegenerative diseases.

Explore how nanotechnology acts as the 'Convergence Engine' for AI materials discovery, CRISPR gene therapy delivery, and industrial quantum computing in 2025.