Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

Scientists led by a team at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out how a molecular machine found in mitochondria—the “powerhouses” of ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria allows us to make the fuel we need from sugars, a process vital to all life on Earth.

Pyruvate kinase occupies a central role in glycolysis, catalysing the conversion of phosphoenolpyruvate to pyruvate with concomitant ATP generation. Its activity is finely tuned by allosteric ...