Protein folding raises some of biology's greatest theoretical challenges. It also lies at the root of many diseases. For example, the fundamental question of whether a protein's final tertiary ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

Most of the activities that go on inside cells—the activities that keep us living, breathing, thinking animals—are handled by proteins. They allow cells to communicate with each other, run a cell’s ...

A landmark study by researchers at the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University reveals how a tiny cellular machine called TRiC directs the folding of ...

Scientists discovered a role played by ribosomes during the folding of new proteins in cells. Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in ...

Artificial intelligence (AI) is reshaping the scientific landscape, offering fantastic solutions to some of the most pressing global challenges. From combating climate change to transforming ...

Protein molecules require a defined shape in order to function. When they are created, their building blocks are therefore linked together in a very specific way. Researchers are now taking a closer ...

"The protein must backtrack in the folding process to correct the mistake, which takes time and is energetically expensive. The demonstration of this mechanism helps expand our understanding of how ...

For those outside the chemistry cognoscenti, the announcement might have seemed little more than researchers patting each other on the back. But the question of protein folding had plagued scientists ...

AlphaFold, DeepMind’s artificial intelligence that predicts the structure of proteins, is a gift to biologists. To understand life, we need to understand proteins. Living things are molecular machines ...