Asymmetric phase-transfer catalysis enables the stereoselective synthesis of chiral molecules by shuttling ionic reagents across immiscible phases under the influence of a chiral catalyst. Typically ...
The Suzuki-Miyaura coupling is a widely used C-C bond forming reaction. Numerous mechanistic studies have enabled the use of low catalyst loadings and broad functional group tolerance. However, the ...
I think VTVT is a largely underfollowed T1D catalyst story, with Phase 3 CATT1 cadisegliatin topline expected in 2H2026. Cadisegliatin’s Phase 2 SimpliciT-1 showed HbA1c improvement, fewer severe ...