NFL Week 12 Fantasy Football
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Predictions, picks and odds for NFL Week 12 game
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NFL DFS: Optimizer reveals Week 12, 2025 daily Fantasy football picks for DraftKings, FanDuel
There are no international games in Week 12, so 11 more NFL games are set for Sunday afternoon either in the 1 p.m. ET or 4:05/4:25 p.m. ET window. Those matchups comprise what is considered the main slate for NFL DFS sites like FanDuel and DraftKings.
With the NFL heading into the home stretch of the 2025 season, several teams needed to pick up crucial wins as they jockey for playoff position.
The reigning league MVP showed why that was the case. Buffalo's star quarterback had some hiccups early at home against the Tampa Bay Buccaneers, but closed out strong in a 44-32 win. Josh Allen threw for three touchdowns on 317 passing yards and also ran in three for a six-score day.
In a battle of 7-2 teams, it was the Rams who survived a heavyweight showdown in the NFC West. The Seahawks have no one to blame but themselves, as Sam Darnold threw four interceptions in the loss. Los Angeles now has the inside track to win the division, but these teams will go head-to-head again in Week 16 on "Thursday Night Football."
There were several games on the Week 11 docket that ended with the margin of three points or less as Josh Allen helped the Buffalo Bills to a big win over the Tampa Bay Buccaneers.
5. Buffalo Bills (7-3), wild card No. 1: QB Josh Allen's big game Sunday moved Buffalo up one spot in the seeding but got the Bills no closer to the AFC East lead. Tough game in Houston looms Thursday night. Remaining schedule: at Texans, at Steelers, vs. Bengals, at Patriots, at Browns, vs. Eagles, vs. Jets
NFL Power Rankings Based on Super Bowl Odds Odds via DraftKings Sportsbook Los Angeles Rams (+500) LW: No. 1 New England Patriots (+1600) LW: No. 4 Make it eigh
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