In view of its ability to explain the most frequent motor symptoms of Parkinson’s Disease (PD), degeneration of dopaminergic neurons has been considered one of the disease’s main pathophysiological ...

Changes in the brain's cholinergic receptor systems underlie several neuropsychiatric disorders, including Alzheimer's disease, schizophrenia, and depression. An emerging preclinical literature also ...

Before the advent of the amyloid hypothesis in the 1990s, the cholinergic hypothesis offered key clues to the etiology of Alzheimer’s disease. Concentrated in the basal forebrain and projecting ...

Fort Lauderdale, Florida — Young patients with chronic pain who take medications other than opioids to cope with their symptoms may experience cognitive adverse effects from these drugs, a new study ...

A link between anticholinergic drug use and cognitive impairment was recently observed from observational studies on randomized clinical trials. Regenstrief Institute research scientists examined ...

This page lists all known medications that could potentially lead to 'Cholinergic syndrome' as a side effect. It's important to note that mild side effects are quite common with medications. The ...

Factors associated with efficacy of TAS-102 in patients with refractory metastatic colorectal cancer (mCRC). This is an ASCO Meeting Abstract from the . This abstract does not include a full text ...

Anticholinergics are effective for some drug-induced movement disorders and not others because the mechanisms differ. Though patients may present with similar symptoms, not all drug-induced movement ...

The new mechanism of action targets cholinergic receptors instead of the standard dopamine receptors. On Sept. 26, 2024, FDA announced that the agency has approved Bristol Myers Squibb’s (BMS) Cobenfy ...

This page lists all known medications that could potentially lead to 'Cholinergic crisis' as a side effect. It's important to note that mild side effects are quite common with medications. The ...