The controlled activation of cell death pathways triggers an acute, transient inflammatory response that, combined with the efficient phagocytosis of dead cells, ultimately restores tissue homeostasis ...

A new study published in Stem Cell Reports demonstrates how a human stem cell-derived model of the intestine can be used to identify potential therapies for inflammatory bowel disease (IBD), ...

An experimental compound reduced the cell death, inflammation, and organ damage seen with diabetes. Led by NYU Langone Health researchers, a new study in mice showed that a drug candidate prevented ...

Researchers have identified an unexpected mechanism that links age-related stress to the decline of blood-forming stem cells.

(L) Corresponding author Thirumala-Devi Kanneganti, PhD, St. Jude Center of Excellence for Innate Immunity and Inflammation director and Department of Immunology vice chair and (R) and first author ...

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn’s disease, ...

A stem cell-derived intestine model reveals glycyrrhizin as a potential treatment for inflammatory bowel disease.

Research in neuroinflammation has increasingly highlighted the role of non-neuronal cells, such as microglia, astrocytes, oligodendrocytes, endothelial ...

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, ...

Every drop of blood in the human body traces back to a small reserve of stem cells buried inside bone marrow. These hematopoietic stem cells generate red blood cells, white blood cells and platelets ...