Researchers have uncovered a previously hidden layer of complexity in how genes are activated, showing that water molecules ...
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...
New insights into how bacteria control DNA synthesis open the door to next generation antimicrobials
Ribonucleotide reductases (RNR) are indispensable enzymes that convert ribonucleotides to deoxyribonucleotides (dNTPs), the precursors to make up DNA. Because DNA synthesis is fundamental to cell ...
The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and ...
The ability to precisely edit the genomes of bacteria has long been a goal of microbiologists. Such technology would enable ...
A new technique shows DNA binding domains are not central to transcription factor targeting in human cells, unlike in ...
Just like us, bacteria are under constant threat of infection by viruses (called phages). We’ve found that many bacteria are armed with sophisticated viral defence systems powered by reverse ...
Morning Overview on MSN
SNIPE defense lets bacteria destroy phage DNA at the cell membrane
A single protein bolted to the inner membrane of a bacterial cell can shred a virus’s DNA before that genetic material ever reaches the interior. That is the central finding behind SNIPE, a newly ...
Cyanobacteria—ancient microbes that oxygenated Earth and made complex life possible—are still revealing surprises billions of ...
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