Researchers have uncovered a previously hidden layer of complexity in how genes are activated, showing that water molecules ...

Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation. Bacterial infections cause millions of deaths each year, with the global threat ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and ...

The ability to precisely edit the genomes of bacteria has long been a goal of microbiologists. Such technology would enable ...

Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial ...

E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...

Ribonucleotide reductases (RNR) are indispensable enzymes that convert ribonucleotides to deoxyribonucleotides (dNTPs), the precursors to make up DNA. Because DNA synthesis is fundamental to cell ...

A new technique shows DNA binding domains are not central to transcription factor targeting in human cells, unlike in ...

A single protein bolted to the inner membrane of a bacterial cell can shred a virus’s DNA before that genetic material ever reaches the interior. That is the central finding behind SNIPE, a newly ...