A complete and accurate genome assembly is essential to fully understand the genetics and evolution of an organism. For many years, automated algorithms could only produce fragmented assemblies; even ...

After sequencing fragments of DNA to obtain reads, most genomic pipelines follow one of two steps. The reads can be de novo assembled to construct longer stretches called contigs from scratch, with ...

The rapid decrease in the cost of genome sequencing has led to an explosion in the amount of data produced by these experiments, with the raw data usually requiring the most space for storage. The raw ...

This could make complete genome assembly simpler, more scalable and more cost-effective for research worldwide." First author Dr. Dominik Stanojević, Scientist at A*STAR GIS, and Faculty of Electrical ...

Next-generation sequencing (NGS) is widely used for microbiome analysis due to its high-throughput and cost-effective nature. NGS utilizes short read lengths, which allow for more efficient and ...