This is a preview. Log in through your library . Abstract To determine the time course of synaptic differentiation, we made successive observations on identified, nerve-contacted muscle cells ...

Congenital myasthenic syndromes (CMSs) are a heterogeneous group of disorders that affect the safety margin of neuromuscular transmission — the depolarization that is required for propagation of the ...

Sitt Wai Fong, Ian S. McLennan, Andrew McIntyre, Jayne Reid, Kathleen I. J. Shennan, Guy S. Bewick, Lynn T. Landmesser Proceedings of the National Academy of Sciences of the United States of America, ...

Researchers have "engineered" a mouse that can run on a treadmill twice as long as a normal mouse by increasing its supply of acetylcholine, the neurotransmitter essential for muscle contraction. The ...

The muscles of the body move because of signals sent by the nervous system, which also takes in sensory information and relays it to the brain. Muscle and nerve cells meet at the neuromuscular ...

James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill, explains how nerve and muscle signaling in the neuromuscular junction go awry in myasthenia gravis.

A recent review article titled "The Role of Rapsyn in Neuromuscular Junction and Congenital Myasthenic Syndrome" has been published by researchers from Nanchang University in China. Led by first ...

This week we are going to discuss a topic that we had briefly touched on earlier, the neurologic autoimmune conditions: myasthenia gravis and Lambert Eaton Syndrome (LEMS). To review: Myasthenia ...

Syn-AKE is a synthetic tripeptide that emulates the active region of Waglerin-1, a venom component derived from the Temple Viper (Tropidolaemus wagleri). Syn-AKE is a synthetic tripeptide that ...