Alternative reading frame (ARF) and p53 are among the most important tumour suppressors based on their frequent and ubiquitous inactivation in human cancer. The tumour suppressor ARF (p14 ARF in human ...
Tumor suppressor protein p19 ARF (Arf; p14 ARF in humans) functions in both p53-dependent and -independent modes to counteract hyper-proliferative signals caused by proto-oncogene activation, but its ...
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