Duke enters Final Four as a worthy favorite, but how can you ignore Houston's experience, defense and grit? Beware the upset!

Despite turning his left ankle and suffering a right elbow injury, Johni Broome finished with 25 points. His health will be massive for Auburn against the Gators. Florida beat the Tigers 90-81 at Auburn on Feb. 8. Auburn won the regular-season SEC title but Florida won the SEC tournament.

Final Four picks, predictions, odds for Duke Blue Devils vs Houston Cougars NCAA Tournament March Madness game Saturday, April 5, 2025. Who wins game?

Fletcher Loyer scored eight of Purdue's first 10 points and goes into halftime with 12 points after hitting 2 of 3 3s. Milos Uzan leads Houston with 12 points and was the only Cougars starter to score a field goal through the game's first 15 minutes. He already has a season-high in made 3-pointers on a 4-of-6 first-half effort.

Final Four in March Madness is set for San Antonio. Here's what to know about the NCAA games, matchups, TV, channel, streaming and more info.

Florida and Duke  have already secured a spot in San Antonio for the 2025 Final Four. On Sunday, the Gators and Blue Devils will find out their semifinal opponents as champions emerge from the Midwest and South regions in Elite Eight action.

Since March Madness expanded to 64 teams in 1985, the only other year that all four top-seeded teams from their respective regions earned Final Four spots was 2008. That year, Kansas won a national title with an overtime victory over Memphis.

No. 1 seed Duke, led by National Player of the Year candidate Cooper Flagg, will square off against No. 1 seed Houston, while No. 1 seed Florida faces No. 1 Auburn in the national semifinals. Florida will make its first appearance in the Final Four since 2014.

Milos Uzan led all scorers with 22 points on 8-of-17 shooting, none bigger than his last-second layup to win the game. He added six assists and three rebounds and was 6-of-9 from three-point range. Emmanuel Sharp added 17 for Houston.