Pistons vs Celtics predictions and NBA picks for Wednesday, November 26. Detroit wins 14th in a row, covering a modest spread in Boston.

A key Boston Celtics starter will miss Wednesday night's Emirates NBA Cup clash against the mighty Detroit Pistons. Starting center Neemias Queta has emerged a

Bill Simmons showed appreciation for how the Pistons fans have supported their team especially during this amazing start to the season.

Starting center Neemias Queta missed Wednesday’s matchup with the Eastern Conference-leading Pistons with an ankle sprain, and Boston survived without him, holding on for a wild 117-114 victory at TD Garden that snapped Detroit’s 13-game winning streak.

Before stuffing their faces with turkey, the Boston Celtics look to defend home court against the red-hot Detroit Pistons. These storied franchises first faced off in 1948. The Celtics own the all-time record against the Pistons,

Pregame analysis and predictions of the Detroit Pistons vs. Boston Celtics NBA game to be played on November 26, 2025 on ESPN.

In Monday’s victory over the Pacers, Cade Cunningham led the way for the Pistons as he recorded 24 points, 11 rebounds and six assists while Jalen Duren added 17 points and 12 rebounds of his own. Now Detroit will try to extend their winning streak to 14 games on Wednesday night in a tough road matchup against the Celtics.