Full Detroit Lions game-by-game predictions
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Iyer picked the top game for all 32 teams' 2025 schedule and wrote that the Rams' matchups against the Detroit Lions in Week 15, the San Francisco 49ers in Weeks 5 and 10, and Atlanta Falcons in Week 17 will be those respective club's best games of their individual seasons.
Detroit's 2025 slate will be a grind, with 11 games against teams that made the playoffs last season. The team will play eight home games and nine on the road, and will be battle-tested throughout the year for what it hopes is another postseason run.
The Lions have five prime-time games, one less than the max allowed (leaving room in case Week 18 needs a primetime flex, a la in 2024). In total, 12 of their games are on national television, and that’s not including Week 18, which does not have a scheduled time or network yet.
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