BALB/c - Wikipedia
WEBBALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation .
The BALB/c Mouse: Genetics and Immunology | SpringerLink
WEBToday the BALB/c mouse is among the five most widely used inbred strains in biomedical research and a particular favorite in immunology and infectious disease research.
BALB/c Mice | Charles River
WEBThe BALB/c mouse is among the most widely used inbred models used in biomedical research, and is particularly utilized in immunology and infectious disease research. Their ability to produce plasma cell tumors within soft tissue is important in the production of monoclonal antibodies (mAbs).
The BALB/c Mouse Model for the Evaluation of Therapies to Treat ...
WEBMar 3, 2023 · With respect to therapeutic evaluation, the BALB/c mouse model is a robust model of infection, typically using females 6–8 weeks old (Table 1). A target dose of approximately 20–50 LD 50 equivalents achieves an acute, lethal infection.
Different Innate Immune Responses in BALB/c and C57BL/6 …
WEBSep 9, 2020 · The BALB/c-recipient model could be used as a surgical control for corneal transplantation experiments, whereas models using C57BL/6 as recipients with the severe inflammation and the high rejection rate may serve as …
Elucidating different pattern of immunoregulation in BALB/c
WEBJan 15, 2021 · Our data indicate that Treg dominate the regulation of immune responses in BALB/c and F1 mice, while multiple regulatory layers exist in C57BL/6 mice that may compensate for the absence of Treg.
MGI - Inbred Strains: BALB - The Jackson Laboratory
WEBThe strain is particularly well known for the production of plasmacytomas on injection with mineral oil. These tumours form the basis for the production of monoclonal antibodies. Used as a general-purpose strain in many different disciplines. Good breeding performance and long reproductive life-span.
WEBIn the current study we compare the hierarchy of immunoregulatory pathways in BALB/c, C57BL/6 mice and their F1 progeny (BALB/c × C57BL/6). Using multicolor flow cytometry, we show that S....
Are BALB/c mice relevant models for understanding sex-related ...
WEBThis gland plays a critical role in maintaining the tear film, and its dysfunction is a major cause of dry eye disease. To understand the factors that underlie meibomian gland sexual dimorphism and promote dry eye in women, we seek to identify an optimal model for the human meibomian gland.
BALB/c | Taconic Biosciences
WEBOverview. Nomenclature: BALB/cAnNTac. A general purpose inbred strain for many different research disciplines. Often used for the production of monoclonal antibodies using hybridomas of BALB/c spleen cell origin. It exhibits good breeding performance and long reproductive life span.
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